Publications/articles

A patient led, international study of long term outcomes of esophageal atresia: EAT 1.

27 June 2017

Abstract INTRODUCTION: Long term outcomes of esophageal atresia (OA) are poorly understood. The Federation of Esophageal Atresia and Tracheo-Esophageal Fistula support groups (EAT), a collaboration of patient support groups aimed to define patient reported long term outcomes and quality of […] LEARN MORE

Dysmotility in esophageal Atresia: Pathophysiology, Characterization, and Treatment

18 June 2017

Esophageal dysmotility is almost universal after esophageal atresia (EA) repair and is mainly related to the developmental anomaly of the esophagus. Esophageal dysmotility is involved in the pathophysiology of numerous symptoms and comorbidities associated with EA such as gastroesophageal reflux […] LEARN MORE

ESPGHAN-NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia-Tracheoesophageal Fistula

10 April 2017

With improvements in surgical techniques and intensive care treatments, the focus of care of patients born with esophageal atresia has shifted from mortality to morbidity and quality-of-life issues. These patients face gastrointestinal (GI) problems not only in early childhood but […] LEARN MORE

Prevalence of Barrett Esophagus in Adolescents and Young Adults With Esophageal Atresia

30 December 2016

Objective: To study the prevalence of Barrett esophagus (BE) (gastric and/or intestinal metaplasia) in adolescents treated for esophageal atresia (EA). Summary of Background Data:  EA patients are at high risk of BE. Methods: This multicenter prospective study included EA patients […] LEARN MORE

Dysphagia in children with repaired oesophageal atresia

30 December 2016

Dysphagia is a common problem in children with repaired oesophageal atresia (OA). Abnormalities in the oropharyngeal and oesophageal phase have hardly been studied. The aims of this study were to assess the prevalence of dysphagia in children with repaired OA […] LEARN MORE

France: a national register for esophageal atresia patients

09 July 2016

A National Esophageal Atresia Register was created in 2008 by the National Reference Center for Esophageal Congenital Abnormalities created in 2006. Primary goal was estimation of live birth prevalence in France. A national network of surgeons and pediatricians was initiated […] LEARN MORE

In-vivo oesophageal regeneration in a human being by use of a non-biological scaff old and extracellular matrix

09 July 2016

Background Tissue-engineered extracellular matrix populated with autologous pluripotent cells can result in de-novo organogenesis, but the technique is complex, not widely available, and has not yet been used to repair large oesophageal defects in human beings. We aimed to use […] LEARN MORE

Circumferential esophageal replacement using a tube-shaped tissue-engineered substitute: An experimental study in minipigs

22 September 2015

Esophageal replacement by the colon or the stomach for malignant and nonmalignant esophageal diseases exposes to significant morbidity and mortality. In this setting, tissue engineering seems to be a seductive alternative. Methods. In a porcine model, we performed a 5-cm-long […] LEARN MORE